Microwave-assisted fibrous decoration of mPE surface utilizing Aloe vera extract for tissue engineering applications
نویسندگان
چکیده
Developing multifaceted, biocompatible, artificial implants for tissue engineering is a growing field of research. In recent times, several works have been reported about the utilization of biomolecules in combination with synthetic materials to achieve this process. Accordingly, in this study, the ability of an extract obtained from Aloe vera, a commonly used medicinal plant in influencing the biocompatibility of artificial material, is scrutinized using metallocene polyethylene (mPE). The process of coating dense fibrous Aloe vera extract on the surface of mPE was carried out using microwaves. Then, several physicochemical and blood compatibility characterization experiments were performed to disclose the effects of corresponding surface modification. The Fourier transform infrared spectrum showed characteristic vibrations of several active constituents available in Aloe vera and exhibited peak shifts at far infrared regions due to aloe-based mineral deposition. Meanwhile, the contact angle analysis demonstrated a drastic increase in wettability of coated samples, which confirmed the presence of active components on glazed mPE surface. Moreover, the bio-mimic structure of Aloe vera fibers and the influence of microwaves in enhancing the coating characteristics were also meticulously displayed through scanning electron microscopy micrographs and Hirox 3D images. The existence of nanoscale roughness was interpreted through high-resolution profiles obtained from atomic force microscopy. And the extent of variations in irregularities was delineated by measuring average roughness. Aloe vera-induced enrichment in the hemocompatible properties of mPE was established by carrying out in vitro tests such as activated partial thromboplastin time, prothrombin time, platelet adhesion, and hemolysis assay. In conclusion, the Aloe vera-glazed mPE substrate was inferred to attain desirable properties required for multifaceted biomedical implants.
منابع مشابه
Various parameters in the preparation of chitosan/polyethylene oxide electrospun nanofibers containing Aloe vera extract for medical applications
Objective(s): The present study aimed to fabricate chitosan/polyethylene oxide (CS/PEO) electrospun nanofibers loaded with Aloe vera extract for biomedical applications. The polymer-to-extract ratio and electrospinning parameters (applied voltage and nozzle-to-collector distance) were evaluated in order to optimize the process of nanofiber fabrication. Materials and Methods: The character...
متن کاملAloe Vera for Tissue Engineering Applications
Aloe vera, also referred as Aloe barbadensis Miller, is a succulent plant widely used for biomedical, pharmaceutical and cosmetic applications. Aloe vera has been used for thousands of years. However, recent significant advances have been made in the development of aloe vera for tissue engineering applications. Aloe vera has received considerable attention in tissue engineering due to its biode...
متن کاملTHE EFFECT OF ALOE VERA HYDROALCOHOLIC EXTRACT ON SPERMATOGENESIS PARAMETERS AND HISTOLOGICAL CHANGES IN THE TESTIS OF RATS FED WITH A HIGH-FAT DIET
Background & Aims: Diseases caused by high-fat diets and obesity are now recognized as a health problem. The aim of this study was to evaluate effect of aloe Vera hydroalcoholic extract on spermatogenesis parameters and tissue structure of testis of rats fed with a high-fat diet. Materials & Methods: 40 adult male Wistar rats were randomly divided into 5 groups (control group (Con), control gr...
متن کاملHistologic and Histomorphometric Study on the Effect of Hydro-Alcoholic Aloe Vera Extract on Tissue Formation of Sciatic Nerve in Diabetic Male Rats
Background & Objective: Diabetes mellitus affects the metabolism of carbohydrates, lipids, and proteins, which leads to the dysfunction of the central and peripheral nervous system. Reports suggest that Aloe Vera has anti-diabetic effects. Therefore, this study was carried out to determine the effect of hydro alcoholic extract of Aloe Vera on Sciatic nerve of the diabetic rats.Materials ...
متن کاملThe Effect of Co-administration of Aloe vera Gel and Cinnamon zeynalicum Hydroethanolic Extract on Wound Healing Process in Diabetic Mice
Objective-This study was conducted to evaluate the effect of co-administration of Aloe vera gel and cinnamon zeynalicum bark hydroethanolic extract on process of wound healing in diabetic mice model.Design- Experimental Study.Animals- Seventy-two male BALB/c mice.Procedures- A single full-thickness excisional wound was created on ba...
متن کامل